Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight

Lower Bone Mineral Density is Associated with Intertrochanteric Hip Fracture

Background: A better understanding of how bone mineral density and vitamin D levels are associated with femoralneck and intertrochanteric hip fractures may help inform healthcare providers. We asked: 1) In patients age ≥ 55 years,is there a difference in quantitative ultrasound of the heel (QUS) t-score between patients with fractures of the femoralneck and those with fractures of the intertroc...

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

Inflammation, fracture and bone repair.

The reconstitution of lost bone is a subject that is germane to many orthopedic conditions including fractures and non-unions, infection, inflammatory arthritis, osteoporosis, osteonecrosis, metabolic bone disease, tumors, and periprosthetic particle-associated osteolysis. In this regard, the processes of acute and chronic inflammation play an integral role. Acute inflammation is initiated by e...

Evidence Report: Risk of Bone Fracture due to Spaceflight- induced Changes to Bone

Chapter 2 Fracture Repair and Bone Grafting

Fracture healing involves a highly integrated sequence of events through which bone is restored to its preinjured condition. The events that occur during healing have been classically divided into four phases: inflammation, soft callus, hard callus, and remodeling (Figure 1). Initially, during the inflammatory stage, a hematoma forms in response to the trauma, and the inflammatory cells in the ...